Objective: We aimed to determine the maximum safe spatial-peak pulse-average intensity (ISPPA) of low-intensity focused ultrasound stimulation (LIFUS) in stroke patients and explore its effect on motor learning and corticospinal excitability.Methods: We adopted the classic 3 + 3 design to escalate ISPPA (estimated in-vivo transcranial value) from 0
To elucidate the role of centriolar satellites in ciliogenesis, we deleted the gene encoding the PCM1 protein, an integral component of satellites.PCM1 null human cells show marked defects in ciliogenesis, precipitated by Cutlery Tray the loss of specific proteins from satellites and their relocation to centrioles.We find that an amino-terminal dom
BackgroundAn estimated 87% of torture survivors experience chronic pain such as brachial plexopathy from upper extremity suspension or lumbosacral plexus injury from leg hyperextension.However, a vast majority of pain is undetected by evaluators due to a lack of diagnostic tools and confounding psychiatric illness.This diagnostic gap results in exc
The conceptual and ritual background of symbolism in the prehistoric art of Anatolia should be investigated within the socio-economic background of the pertinent Maca Neolithic and Chalcolithic societies.Since the adoption of farming did not totally replace the more traditional modes of subsistence, it is doubtful that the supernatural world-order
Cancer vaccines represent a promising approach within immunotherapies.These vaccines are tailored to target tumor-specific antigens, thereby offering a precision approach to cancer treatment.The key principles in developing therapeutic cancer vaccines include identifying appropriate vaccine targets and selecting effective vaccine delivery platforms